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Several complex signal transduction pathways and cellular processes have been implicated in APAP hepatotoxicity, including those involving c-Jun N-terminal kinase, Nuclear factor E2-related factor 2 (Nrf2), p53, endoplasmic reticulum stress, autophagy, and sterile inflammation (Chowdhury et al

It was found that the administration of ferroptosis inhibitors partially protected neurons from death in the middle cerebral artery occlusion (MCAO) model (Weiland et al., 2019)

The selection of solvent system, working concentration, and downstream handling is determined by the researcher according to the requirements of the specific analytical or in-vitro protocol